Bioinformatics Pipelines in AWS
Deploying Nextflow experiments in AWS
Mark Preston
"Thanks to Crunchloop’s efforts, the app met testing requirements and received positive feedback from end clients and prospects. The team seamlessly integrated their process to the client's methodology, and internal stakeholders were impressed with the vendor's work ethic."
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Service
Team
Technology
Industry
Who is
Prismea
?
Prismea specializes in providing bioinformatics, cloud infrastructure, and compliance services for biotech companies. They excel in data analytics, cloud integration, and automation of scientific data workflows. Their solutions ensure security, privacy, and intellectual property compliance, enabling clients to enhance team skills, scale infrastructure, and maintain robust compliance processes.
Challenge
Prismea approached us with the need for an automated solution to deploy scalable bioinformatics pipelines in AWS. They required the implementation to be done using CloudFormation and needed the infrastructure to be ephemeral, ensuring environments could be deployed for experiments and then destroyed to minimize costs. Key requirements included:
• Ephemeral infrastructure for cost-efficiency
• Security measures (limiting internet access, independent networks)
• Minimum permissions granted within AWS
• Use of Nextflow for bioinformatics algorithms
Solution
Strengthening Security with Least Privilege and Isolation
The architecture emphasized security by limiting internet access and creating independent networks for different components. We also enforced the principle of least privilege, granting minimum necessary permissions for all AWS interactions, thereby enhancing the security posture of the solution.
Things we love
The implementation provided Prismea with a scalable, secure, and cost-effective solution for running bioinformatics pipelines. The solution’s ephemeral infrastructure allowed for efficient resource usage, and the custom CLI facilitated easy deployment and management of experiments. The architecture ensured data security and adhered to AWS best practices, making it an optimal solution for Prismea’s needs.
Bioinformatics Pipelines in AWS
Deploying Nextflow experiments in AWS
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